HuCAL® Antibodies Technical Manual
20 July 2007
Antibodies by Design delivers custom monoclonal antibodies in eight to ten weeks, using MorphoSys HuCAL GOLD recombinant monoclonal antibody technology.
The company has now released the HuCAL technological manual, to assist all users of the monoclonal antibodies it supplies.
This valuable 84 page publication describes the principles behind HuCAL recombinant antibodies and the basis of their exceptional specificity. As well as presenting examples and troubleshooting tips for the use of protocols in applications such as western blotting, ELISA, IHC, IP and flow cytometry.
HuCAL technology has been revolutionizing the way monoclonal antibodies are generated for many years and offers lots of advantages over traditional animal-based methods. These include speed, specificity and production technology. HuCAL antibodies are selected from a high quality, synthetic library of more than 15 billion expressible antibody specificities. This is the very latest and most powerful library created by MorphoSys and has already generated thousands of monoclonals for researchers worldwide.
In addition to explaining the key design and construction features of the HuCAL library, the technical manual explains why HuCAL antibodies are preferable to full IgGs for IHC, cell isolation and even protein crystallization. It also explains how the selection can be geared to directly generate a monoclonal antibody that can distinguish between a wild-type protein and a single amino acid mutation; and why using the AgX™ antigen expression service can lead to increased specificity and functionality for your antibodies.
Copies of this essential publication for all antibody users are shipped with all HuCAL antibodies, can be downloaded or requested as a hard copy.
