Contract Research Organisations


Acumen is dedicated to the early development of medicines and has a rapidly growing reputation as an innovative phase I/III contract research organisation.

The high quality, flexible and fully integrated clinical development services have been developed to assist clients with accelerated start up and rapid development of their drug development lifecycle.

Acumen is a team of fully trained, dynamic and flexible clinical research professionals, physicians, research nurses and project managers with a strong work ethic, who are widely respected and experienced in all aspects of pharmaceutical contract research.

The clinical research unit provides excellent facilities for both short and long-term residence; this together with our careful screening selection procedures ensures that we have an enviable reputation for patient and healthy volunteers successfully completing studies.

Acumen has also actively recruited patients for multicentre phase III clinical trials, acting as a central site and often aided in the rapid recruitment/conduct of patient studies in collaboration with other larger contract research organisations.


Adesis is a multi-dimensional contract research organization (CRO) specialising in organic synthesis, for milligrams to kilogram quantities, for the life sciences and biomaterials industry.

Outsourcing should be a strategic component of any sponsor’s research and development portfolio, instead of an ad hoc decision.

In medicinal chemistry, this strategy allows in-house chemists to focus on the design and assembly of new lead molecules versus routine syntheses which can be outsourced.

Full time equivalents (FTE’s) are committed full time to the sponsor. FTE-based projects are quoted on time and materials, with back-charge of raw materials.

One-off projects are typically more traditional Kilo Lab projects involving large quantities of material.


Almac Sciences is involved in many activities including milligram to multi tonne synthesis, and synthesis of potent and cytotoxic compounds.

Almac Clinical Technologies provide Interactive Voice and Web Response Systems (IXRS™ ) for patient tracking - patient randomisation includes centralised randomisation, stratified randomisation and adaptive / balancing algorithms.

Almac Clinical Services provides a global service for the manufacture, packaging and distribution of clinical supplies.

Almac Diagnostics provide a generation of novel disgnostic products to improve patient management.

ALS laboratory
The purpose-built ALS laboratory in Luleå, Sweden, houses eight HR-ICP-MS instruments.
Research focused on clinical applications
Trace metal monitoring is performed under cleanroom conditions.
HR-ICP-MS instruments
HR-ICP-MS instruments offer detection at low ppt levels.
Trace metal monitoring
Our chemists perform research focused on clinical applications and isotopes.

Non-invasive imaging
Non-invasive imaging allows the visualisation of structures, functions and dysfunctions in the whole body, for research purposes.
Physiopathology of bones and bones metastasis
Animascope has a robust expertise in studies on physiopathology of bones and bones metastasis.
Studies of reproductive medicine
At Animascope, expertise and access to medical imaging technologies are readily available, such as for studies of reproductive medicine.
Non-invasive 3D-imaging techniques
Animascope is a specialist in non-invasive 3D-imaging techniques such as X-ray computed tomography (CT) for studies of hard and soft tissues.
Whole-body multimodality studies
Whole-body multimodality studies can be performed on healthy and disease animal models, in many species. (Image courtesy of Siemens Molecular Imaging.)

Hansenula yeast expression
The Hansenula expression system offered by ARTES strikes with high yield, high robustness and high reliability resulting in cost-efficient production processes.
Lab-scale process development
Lab-scale process development for technology transfer to manufacturing sites.
Biopharmaceutical documentation
Documentation for registration purposes.


BEBAC specialises in providing biostatistical services, contractor selection and supervision.

We are able to support our clients both in the planning stage and in the evaluation of studies, responding deficiency letters, as well as preparation for regulatory hearings, placement and evaluation of CROs.

Pre-clinical efficacy studies
Biomodels provides pre-clinical efficacy studies for drug development.
Cancer supportive care
We have particular expertise in cancer supportive care and pre-clinical models relating to the side effects of chemotherapy and radiation treatments.
Biomodels customized programs
We provide customized programs to demonstrate efficacy data (non-GLP) for regulatory submissions.
Endoscopy
Endoscopy - normal colon.
Endoscopy - IBD colon
Endoscopy - IBD colon.

Human colon epithelium
Healthy human colon epithelium – merge of three labellings.
Optical microscope image of specific Phloxine-tartrazine labelling
Mouse small intestine showing labelled Paneth cell secretory granules; optical microscope image of specific Phloxine-tartrazine labelling on a paraffin-embedded section of the intestinal crypts or Lieberkühn glands.
Human vascular endothelial cells
Human vascular endothelial cells 24h after TNFalpha-induced inflammation phalloidin-TRITC and ICAM-1 labelling.
Biological imaging equipment
Thanks to our partnership with Olympus France our imaging platform is equipped with ground-breaking biological imaging equipment: next generation HD microscopy, image acquisition and support technologies.
Quantification of the effects of active biological agents
Biomarker solutions for drug success: quantification of the effects of active biological agents on different cellular targets in human and animal tissue as well as cell culture.

Biopharmaceutical contract manufacturing
Biovian is a one-stop-shop that provides cGMP contract manufacturing of biopharmaceuticals.
Aseptic filling and finishing
We offer a wide range of services from early development to aseptic fill and finish.
cGMP facilities
Biovian’s cGMP facilities and state-of-the-art equipment enable flexible pilot production and development services.
Biovian’s cGMP facilities
Biovian’s 1,600m² cGMP facilities contain EU grade A, B, C and D class clean rooms and warehouses under full quality control, as well as extensively equipped development laboratories.

Biovian offers aseptic filling and finishing services.

Cerebricon preclinical laboratories
Cerebricon has its own scientists, preclinical laboratories and animal facilities for CNS drug development; this includes a 7.0 Tesla MRI for small animal imaging including pharmacological MRI (phMRI) for use with in vivo, in vitro and ex vivo models of CNS and PNS disease.
Images of Pharmacological MRI study
Pharmacological MRI (phMRI) is a new method used for the noninvasive preclinical study of drugs aimed at CNS diseases like Alzheimer’s, Parkinson’s and stroke; it is also used for the study of psychiatric diseases. Here we see the in vivo signal created by the iv introduction of nicotine by a specific area in the cortex of the brain.
Image of a Cerebricon’s laboratory
Cerebricon’s laboratories are fully equipped to run multiple studies in parallel, while Cerebricon’s internal quality assurance programme ensures that studies and results adhere to the highest possible standards; where possible Cerebricon studies are automated. Cerebricon can run preclinical rodent studies with small numbers of animals all the way up to very large cohorts.
Image of a amyloid beta plaques from the hippocampus of a transgenic mouse
The ability of a CNS CRO to provide behavioural modelling and the most pertinent transgenic model, as well as imaging and histological services all under one roof, is very important. Here we see a close up of amyloid beta plaques from the hippocampus of a transgenic (TG2576) mouse; this was done with immunohistochemical detection in Cerebricon’s laboratories.
Image of the mitochondria of cortical neurons stained with Mitotracker
Cerebricon’s in vitro cell laboratories carry out many studies involving primary cortical neurons and also neurite outgrowth assays (NOG); in this picture we see the mitochondria of cortical neurons (orange areas) stained with Mitotracker.

Non-clinical studies monitoring
High quality monitoring of non-clinical studies.
Nonclinical drug development
Nonclinical drug development services in safe hands.
En route to novel medicines
En route to novel medicines.
Henk Tennekes
Henk Tennekes provides toxicology and nonclinical drug development services that you can rely on.
High-quality nonclinical drug development
Henk Tennekes' considerable experience in toxicology enables him to provide high-quality nonclinical drug development services and toxicology consultancy services.

Clinical data analysis service
Exploristics provides a clinical data analysis service.
Clinical data exploration
We use a broad range of tools for clinical data exploration, mining and modelling.
Clinical application of biomarkers and pharmacogenomics data
We are experts in the clinical application of biomarkers and pharmacogenomics data.
Biomarker data management
We supply and distribute biomarker data management, visualisation and analysis tools in Europe.

Clinical contract research organization
ikfe CRO is an international service provider in the area of clinical contract research.
Multinational clinical research projects
Core competences: consulting, organisation and conduct of multinational clinical research projects.
Chronic metabolic disorder of diabetes mellitus
Our main focus is the chronic metabolic disorder of diabetes mellitus.
GCP Training
We can offer you comprehensive and ethics-committee-reviewed GCP training to ensure the qualification of your study site.


We address customer specific analytical questions for analytical services for pharmaceutical quality control.

We are your competent partner for all enquiries about analytical services for pharmaceutical quality control.

Amino acid analysis according to the Ph Eur is a complex procedure requiring long experience.

For vitamin analysis we exclusively use chromatographic and mass spectrometric methods.

Structure elucidation of unknown impurities requires a multi-step approach.


From first discussions with a client through to the achievement of project deliverables, InSymbiosis' proven project management process ensures projects are executed and delivered on time and on budget and at the highest scientific standards.

InSymbiosis’ drug discovery services cover the complete discovery process, from validation of a drug target through to optimization of a lead compound.

At InSymbiosis, our substantial experience in preclinical chemical optimization and chemistry, manufacturing and control (CMC) can facilitate our clients’ transition through lead optimization to the development and optimization of a clinical candidate.

InSymbiosis is able to provide GLP-compliant toxicology and safety pharmacology services, including the management and monitoring of these important studies.

Working in symbiosis towards your therapeutic goals, our team of experts will accelerate your progress and compliment your core strengths; InSymbiosis: your first choice in partner.

Contract manufacturing and development
Kemwell has extensive expertise in contract manufacturing and development services for pharmaceutical products.
Pharmaceutical development labs
The staff at Kemwell’s pharmaceutical development labs have developed formulations and analytical methods for conventional and specialised dosage forms.
formulation and process development
We offer formulation and process development, development and validation of analytical methods, clinical supply, scale-up, process validation, and stability studies.
Oral healthcare R&D centre
In partnership with a leading pharmaceutical company Kemwell has set up an oral healthcare R&D centre.
EU gateway release testing
Our development services include EU gateway release testing, stability studies, and transfer of analytical methods.

Marin Biologic Laboratories
Marin Biologic Laboratories is a contract research organization (CRO) that provides custom research and development as well as GLP and GMP compliant assay development, validation and testing services for the pharmaceutical, biotechnology, diagnostic and agricultural industries.
Marin Biologic Laboratories
What distinguishes Marin Biologic from other contract laboratories is a breadth of scientific knowledge, our client communication and our flexibility.
Tackle complex projects
We blend the fields of cell biology immunology, molecular biology and biochemistry to tackle complex projects in an innovative and timely manner.


Millennium Research Laboratories (MRL), was founded in 2002 by a founding group that possess decades of combined experience in the fields of polymer science, advanced materials, drug discovery, and development.

MRL offers a wide spectrum of services and expertise in scientific, professional, technical, manufacturing, quality control, and regulatory fields.

MRL's understanding of the cost pressures in today’s pharmaceutical environment ensure that we develop products that can be manufactured in a timely and reproducible manner using cost effective materials.

Biomarker discovery
Biomarker discovery.
Biomarker assay development
Rapid biomarker assay development.
Biomarker testing
Biomarker testing.
Protein multiplex assay
CSF 19-protein multiplex assay – test samples now!

Contract research organisation
NORMA is a contract research organisation that conducts clinical trials in northern Europe.
pharmaceutical and biotech clinical trials
NORMA conducts phase I–IV clinical trials for pharmaceutical and biotech companies.
NORMA clinical trials
NORMA has participated in over 300 clinical trials across a range of therapeutic areas.
Clinical trials
NORMA is a flexible and co-operative business partner for clinical trials.
Contract research organisation
NORMA has a reputation as a trusted contract research organisation for clinical trials.


Norwich Clinical Research Associates (NCRA) is a competitively priced, flexible contract research organization (CRO) with the industry, regulatory, and clinical expertise to see clinical development from all sides of the process.

Norwich Clinical Research Associates will provide rapid, accurate, cost-effective services to the pharmaceutical, medical device and nutraceutical industries, meeting the industries’ specific outsourcing needs for quality clinical research.

Specialising in Phase I-IV pharmaceutical and 510(k) through PMA clinical studies for product development, NCRA conducts in entirety small to large clinical trials from protocol design to completion of the final reports for regulatory submission.

Notox sites located in Hertognbosch
An overview of Notox sites located in Hertognbosch, the Netherlands.
Cleaning the building sites, Hertogenbosch
Cleaning the building sites, Hertogenbosch, the Netherlands, July 08.
Overview of vivarium, laboratory and office space
Facts & figures: overview of vivarium, laboratory and office space.
Preclinical development
Preclinical development.
Toxicology research services
Toxicology research services.

Contract research organisation
OnQ Research is a full service South African contract research organisation that offers services to assist with the entire continuum of clinical research.
Clinical research
OnQ Research is a contract research organisation with experience in many areas of clinical research.
International clinical trial project management
OnQ Research’s staff has international clinical trial project management experience.
Clinical trials in South Africa
South Africa is an excellent location for clinical trials as it offers varied patient populations and therapeutic areas.
OnQ Research facilitates
OnQ Research facilitates the development of skilled clinical research sites in locations across Africa.

Patheon - contract development company
Patheon is a leading global provider of contract development and manufacturing services to the pharmaceutical industry.
The Patheon 4•6•8 Promise
The 4·6·8 Promise™ ensures that Patheon will have your projects completed in the fastest possible timeframe, without compromising the high standards of work you demand.
Phase I clinical trial materials
Offering accelerated delivery of Phase I clinical trial materials.
Accelerated pharmaceutical development
Leading the way in accelerated pharmaceutical development and product transfer.
Pharmaceutical development Services
Please click to see an enlarged version of the matrix.

Research pharmacology
Research pharmacology provides proof of concept for drug efficacy.
Pipeline Biotech's experienced staff
Our experienced staff provides quality results of a high technical standard.
FELASA guidelines
The health status of laboratory animals is monitored according to FELASA guidelines.
Pipeline Biotech
We are GLP and GMP compliant, and certified and audited by the National Medicines Agency in accordance to the OECD guidelines.

Image of a sampling molecules
Sampling molecules by in vivo microdialysis.
Image of a Microdialysis graph
Microdialysis is a major tool in functional pharmacology and evaluation of CNS drugs.
The effect of repeated forced swim test
Functional/neurochemical evaluation of mouse phenotype: the effect of repeated forced swim test on noradrenlaine levels in the hippocampus of wild-type and galanin-overexpressing mice (PNAS, 2004).
Rat striatum by HPLC with electrochemical detection
Determination of DA, NA, 5-HT and their metabolites in the rat striatum by HPLC with electrochemical detection.


GMP chemistry and isotope synthesis.

In vitro metabolism.

Bioanalysis and central lab.

Microbiology.

Drug discovery
The Infodix staff has over 80 years of experience in discovery informatics, and consists of computer science, chemistry and pharmacology specialists, including research directors, bio and chemoinformaticians, application programmers and chemists.
NIPER campus in Chandigarh
Biodix is located within the NIPER campus in Chandigarh, India, which is a central national campus for pharmaceutical sciences; it's on a 130-acre site that has excellent transport connections by air, train or highway.
GLP-compliant rodent laboratory
The Toxis facilities include 2,000m² GLP-compliant rodent laboratory facilities; access is restricted to Toxis and animal care personnel and the facilities are monitored by veterinary surgeons and GLP-certified technicians.
SBW Extranet services
Customers will be provided with secure, authorised and monitored access to SBW Extranet services for progress reporting and data transfer; this service is accessible via an SSL-secured website.
SBW drug research
In addition to providing services SBW acts as your strategic partner in drug research, providing you with comprehensive solutions to get the best out of your research efforts.

Salt screening
Solid Form Solutions' salt screening approach has been developed from many years' experience in the pharmaceutical industry.
Polymorph screening protocol
Solid Form Solutions' polymorph screening protocol provides a clear understanding of the polymorphic space around an API and identifies the polymorphic form for further development.
Batch process optimisation
Batch process optimisation provides an optimised process and low-risk route to manufacture.
synthetic chemistry services
Solid Form Solutions’ synthetic chemistry services can be used standalone or integrated with the screening services as part of a complete early chemical development programme.

TRANSIL ready-to-use assay kits
TRANSIL® ready-to-use assay kits are smart dialysis systems that use an immobilised biological matrix with a very large surface area.
Brain absorption kit
Sovicell's brain absorption kit is a ready-to-use assay kit that assesses how drug candidates pass across the blood-brain barrier.
The TRANSIL ready-to-use plasma protein binding kit
The TRANSIL ready-to-use plasma protein binding kit is designed to assess the binding of drugs to plasma binding protein.
TRANSIL intestinal absorption kits
The TRANSIL ready-to-use intestinal absorption kit is designed for rapid assessment of drug candidates' ability to cross the intestinal epithelium.
TRANSIL high-protein binding assays
The TRANSIL high-protein binding assay is based on the partitioning of the test item between the plasma and membrane.

Medicinal chemists with drug discovery experience
Sygnature's pharmaceutical industry-experienced medicinal chemists have considerable drug discovery experience.
Sygnature's drug discovery know-how
We contribute resources, chemistry expertise, intellectual input and drug discovery know-how to collaborations.
Sygnature's state-of-the-art laboratories
Sygnature occupies modern, state-of-the-art laboratories in BioCity, Nottingham.
virtual screening and high-throughput chemistry
We can apply virtual screening and high-throughput chemistry to generate molecules with desirable lead-like properties.
Sygnature drug discovery projects
Sygnature works closely with the client's scientists to accelerate compounds into development and increase the value of their discovery projects.

Contract research organisation
Toxikon Europe is a leading contract research organisation that provides high-quality preclinical safety studies to the life science community.
Extractables and leachables testing
Toxikon has vast expertise in extractables and leachables (E&L) testing, and can assist in the assessment of scientific data obtained in E&L studies, via a toxicological risk assessment.
Toxikon Europe
Toxikon Europe cooperates with leading container / closure manufacturers and pharmaceutical companies to help these industries comply with the new requirements of container / closure testing.
Toxikon preclinical testing capabilities
Besides extractables and leachables testing, Toxikon offers a wide range of preclinical testing capabilities for the pharmaceutical industry.
Biopharmaceuticals
Biopharmaceuticals are becoming increasingly important as novel therapeutics for human disease; specialised testing using molecular biology and immunoassay techniques are available as well as animal models to evaluate immunogenicity and immunotoxicology.

Mammalian cell line development
Trenzyme offers highly customised services, from recombinant expression to mammalian cell line development.
Cross organism expression technology
The modular cross organism expression technology platform allows the parallel expression of a given target, from E. coli to mammalian cell lines, exploiting the benefits of each host system.
ExoIN technology
Due to the ExoIN technology stable, homogeneous cell lines with tunable target expression can be generated within weeks instead of months.
cytobox
cytobox™ offers easy online ordering of stable customised cell lines, from gene synthesis to stable CHO or HEK293-based cell lines, within 30 business days – timeline and target expression guaranteed.


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