Conditioned Place Preference Test
21 March 2007
Neurofit is now pleased to be able to offer the rat Conditioned Place Preference (CPP) test to its customers. The CPP test is able to evaluate the abuse potential of compounds and it is therefore an important study to include in the development of a new compound or in the evaluation of a new target.
Neurofit has developed a semi-automatic test to evaluate CPP in the mouse.
CPP is a well-accepted model to evaluate preferences for a specific environment that has been associated with a positive reward or drug such as morphine. In the test, a positive stimulus is paired with placement into a specific environment. This procedure is repeated for several days after an initial conditioning phase, during which the animal is allowed to explore the whole environment. After these steps, the animal is allowed to move freely in the whole apparatus and the time spent in the compartments previously associated with the stimulus can be used as an indicator of preference and a measure of reward learning.
Neurofit also offers a range of validated in vitro and in vivo screening tests for psychiatry, neurology and ophthalmology.
