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Stability Analysis of Proteins for the Biopharmaceutical Industry Friday, September 02, 2016 The biggest class of biopharmaceuticals on the market is monoclonal antibodies (mAb) and their specific binding nature provides an opportunity to use them to modulate...

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Using Differential Scanning Calorimetry in Lipid Bilayer Membranes to Characterise Thermotropic Phase Transitions Friday, September 02, 2016 Proteins and other constituents are bound or incorporated into cell membrane surface bilayers formed by...

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Save Money with the Mastersizer 3000 Thursday, July 14, 2016 Certain practical criteria must be met by an instrument to be used in today's busy analytical laboratories. It must also stand-up to rigorous economic...

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Reasons to Replace Your Viscometer with a Rheometer Wednesday, July 13, 2016 It may be time to assess what a modern rheometer can do, especially in comparison to a...

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Using Isothermal Tirtration Calorimetry to Perform Biophysical Characterisation of Epigenetic Protein Interactions with Chromatin Wednesday, July 13, 2016 Epigenetics is the study of heritable changes in gene expression caused by non-genetic mechanisms, without alternations in gene structure or DNA...

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Preformulation and Stability Studies of Biotherapeutics by DSC Wednesday, July 13, 2016 Treating diseases using Biothermics is a rapidly growing field, often requiring high-concentrations and multiple...

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Using Different Scanning Calorimetry to Accelerate Biotherapeutic Process Development Wednesday, June 08, 2016 Purification and production of immunoglobulins of the gamma isotope for therapeutic or diagnostic applications is commonly used, particularly human...

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Use of Fully Automated Scattering Techniques to Identify Protein Formulations Tuesday, June 07, 2016 To meet commercial targets, fully-automated light scattering techniques are sometimes used in the identification of...

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Binding Thermodynamics of Substituted Diaminopyrimidine Renin Inhibitors Wednesday, February 24, 2016 ACE inhibitors reduce blood pressure by inhibiting production of the potent vasoconstrictor angiotensin II and ARB inhibitors block binding of angiotensin II to the angiotensin...

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Exosomes and Microvesicles: Characterization by Nanoparticle Tracking Analysis (NTA) Monday, January 11, 2016 NTA uses the properties of both light scattering and Brownian motion in order to obtain the particle size distribution of samples in liquid suspension....