Bioinformatic Services and Gene Libraries
13 December 2007
A gene is more than a piece of DNA, much like a gene cluster is more than just an assembly of genes and like a gene like is more than a permutation - it's like the spirit of its design.
New bioinformatic services at ATG:biosynthetics: we now offer extended generation of structure based gene libraries for the efficient functional optimizations of the proteins and riboswitches in your processes. Starting from comparative sequence and structural protein and RNA data ATG offers the creation of rational to semi-rational gene libraries.
For riboswitches this means complex libraries of candidate switches for screening.
For enzymes this means improved activity, physical and chemical stability, specificity, selectivity etc. Reduction and down-grading of library complexities by calculating each amino acid position according to structure, required space and chemical properties. The amino acids are calculated individually and ranked by probability.
