Genomics and Proteomics
| ATG Biosynthetics | ||
Gene synthesis offers the opportunity for generating, very systematically, sub-molecular peptide libraries. |
Demonstration of the specificity of primary structure binding of mAB1 and mAB2 by clear positives. |
pEPSCAN / pEPMAP peptide libraries from ribosomal synthesis can be derived from any protein of your choice. |
Schematic representation of bacterial clones presenting individual epitopes derived from different regions of the protein they are systematically derived from and expressed with a carrier protein. |
Design of pEpIDENT clones, representing peptide epitopes of different protein domains. |
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| CrossGen | ||
At CrossGen we develop tools that meet the challenges of cross species gene expression analysis; the complexity of extrapolating cross species toxicalgenomic data is simplified. |
Using comparative genome hybridisation, genomic DNA of the subsequence genome is hybridised to a reference GeneChip® array. |
The CrossGen technology provides a cost effective method of selecting the most appropriate animal model for pre-clinical toxicgenomic assessment of drug candidates. |
Cross-platform data variability is necessitated by the variety of microarray technology on the market; CrossGen eliminates cross-platform variability by enabling gene expression analysis on one platform. |
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| Fluoresentric | ||
Full service real-time PCR consultation: sequence discovery, assay design, protocol optimization and project planning. |
Pharmaceutical bioactivity testing: gene expression and biochemical concentration wrapped into one complete drug bioactivity evaluation package. |
Multicolor real-time PCR: multiplex for high-throughput quantification, genotyping and internal positive control development. |
Custom drug sensitivity and resistance testing real-time PCR: from resistance marker discovery to custom ready-to-use kits. |
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| GenXPro | ||
A highly-specific 26bp tag-based approach allows for ultra-deep analysis. |
GenXPro has developed efficient protocols for the preparation and analysis of normalised cDNA. |
By combining SuperTAG-DGE with the sequence information of normalised cDNA, any non-model organism can be analysed quickly and cost effectively. |
GenXPro's SuperSAGE and SuperTAG-DGE platforms are the most advanced derivatives of the SAGE technology. |
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| LOGOPHARM | ||
Plasma membrane proteins of cultured hippocampal neurons visualised by affinity labelling prior to their selective isolation for proteomic analysis. |
The CompleXio platform has been specifically designed for identification of protein-protein interactions in native tissues and cells. |
Upper image: preparation of specialised components of the pain pathway from rat; lower image: ultra-sensitive Western blot analysis of G-protein coupled receptors in membrane samples prepared from the tissues above. |
Multi-Western blot showing the simultaneously but independently purified membrane protein complexes from one sample of solubilised rat brain membrane using the PMAP technology. |
ComplexioLyte solubilisation buffers and MS-validated antibodies – powerful tools for membrane protein research and development. |
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| MicroBioChips | ||
Customers can send their samples for multiplex and high-throughput protein analysis and receive a complete, secured and confidential report of results. |
Clients will benefit from the strong background in proteomic, immunology and protein arrays of MicroBioChips. |
Cytokine expression of cell culture supernatants are profiled on an antibody array. |
Custom-made peptide array can be designed for epitope mapping in vaccine or diagnostic research. |
Serum proteins can be measured in multiplex for diagnostic / pronostic purpose, in preliminary screening, these proteins can be identified by customers in 2D-gel, Maldi-Tof, Seldi-Tof, Lc-Ms or other proteomic or transcriptomic techniques. |
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| Nanoxis | ||
Membrane protein research as simple as one, two, three: isolate, vesiculate and immobilize. |
LPI™ Maxi FlowCell. |
LPI™ HexaLane FlowCell. |
