Genomics and Proteomics
| Fluoresentric | ||
Full service real-time PCR consultation: sequence discovery, assay design, protocol optimization and project planning. |
Pharmaceutical bioactivity testing: gene expression and biochemical concentration wrapped into one complete drug bioactivity evaluation package. |
Multicolor real-time PCR: multiplex for high-throughput quantification, genotyping and internal positive control development. |
Custom drug sensitivity and resistance testing real-time PCR: from resistance marker discovery to custom ready-to-use kits. |
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| Gentris Corporation | ||
Gentris’ accession team verifies the integrity of your samples upon arrival and maintains chain of custody to ensure accuracy in reporting of results. |
Our microarray technology enables you to examine changes in gene expression as well as examine associations between genetic polymorphisms in disease and in drug response. |
Gentris’ data team provides our clients with accurate and useable data by being well-versed in a multitude of assays and technologies. |
Gentris’ compliant biostorage facility includes an enormous bank of freezers as well as ambient temperature storage capabilities to secure your samples in a highly monitored environment. |
Our high-throughput DNA sequencing provides a quick turnkey solution for discovery, genotyping, or validation of assays for our clients. |
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| LOGOPHARM | ||
Plasma membrane proteins of cultured hippocampal neurons visualised by affinity labelling prior to their selective isolation for proteomic analysis. |
The CompleXio platform has been specifically designed for identification of protein-protein interactions in native tissues and cells. |
Upper image: preparation of specialised components of the pain pathway from rat; lower image: ultra-sensitive Western blot analysis of G-protein coupled receptors in membrane samples prepared from the tissues above. |
Multi-Western blot showing the simultaneously but independently purified membrane protein complexes from one sample of solubilised rat brain membrane using the PMAP technology. |
ComplexioLyte solubilisation buffers and MS-validated antibodies – powerful tools for membrane protein research and development. |
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| Tissue Solutions | ||
AD cortex: thioflavine-S stain (20 x). Tissue Solutions has access to a large collection of brain tissues, from neurodegenerative diseases (Alzheimer's, Parkinson's, bipolar disease, depression, ALS, schizophrenia, etc.) and matched controls (specialised staining is also available). |
We can provide rare human tissues; e.g. synovium from controls and rheumatoid arthritis (RA) patients. Above: H&E slides of normal synovium, RA and OA synovium. |
Tissue Solutions provides the full FDA / EMEA panel of normal tissues for antibody cross-reactivity studies. We can provide this in frozen and FFPE format (other species also available). |
Tissue Solutions supplies material for ADME and toxicology studies. |
Fresh and frozen skin for trans-dermal drug delivery, permeation studies and cell extraction: surgical samples from scalp, abdomen, breast and foreskin. |
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| VERTIS Biotechnologie | ||
RNA analysis with a Shimadzu MultiNA microchip electrophoresis system. |
VERTIS's innovative RNA-seq applications for eukaryotic transcriptome analyses. |
VERTIS's innovative RNA-seq applications for prokaryotic transcriptome analyses. |
VERTIS's bioinformatics solutions: mapping of miRNA sequences against the human genome. |
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| Xbrane Bioscience | ||
Xbrane’s Lemo System is the E. coli protein expression system that enables the optimised expression of any protein, including membrane proteins. |
Xbrane’s Lemo System outperforms other systems in protein expression (Xbrane’s Lemo System is the orange bar). |
Xbrane’s protein expression systems enable high yield expression of otherwise host-toxic proteins like membrane proteins. |
Bacterial protein expression systems are attractive because they are inexpensive and offer rapid biomass accumulation. |
Xbrane’s Rhamex System has the ability to express larger amounts of host-toxic and properly folded (active) proteins. |
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