Bruker Daltonics - Advanced Mass Spectrometry Instrumentation

Bruker Daltonics is a leading developer and provider of innovative life science tools based on mass spectrometry. Our integrated solutions combine automated sample preparation; advanced mass spectrometry like ESI-LC/MS, MALDI-TOF, ESI-TOF and FTMS; reagent kits; and bioinformatics for data interpretation and data mining.

Our range of products includes CLINPROT™, PROTEINEER ™, PROTEINEER-LC™and the MALDI Molecular Imager. CLINPROT™ provides a set of tools for clinical proteomics and biomarker discovery; state-of-the-art MALDI imaging is easily feasible with the MALDI Molecular Imager; microorganism identifications are enabled by convincing new technologies based on our MALDI BioTyper; PROTEINEER ™ constitutes a suite for protein identification and characterization from 2D gels; and PROTEINEER-LC™ supports all LC-based proteomics, like LC-MALDI.

An analytical platform for functional genomics studies is represented by GENOLINK™. The METABOLIC PROFILER™ is an integrated platform for metabolism studies and pharmaco-metabolomics.

ION TRAP / ESI-LC MS - EVALUATION OF COMPLEX MIXTURES IN PROTEOMICS, DRUG DISCOVERY AND METABOLIC PROFILES

HCT and HCTultra (high capacity trap) - an ultra-high performance ion trap mass spectrometer for dramatically faster and more sensitive analysis in proteomics and metabolomics.

HCTultra PTM DISCOVERY SYSTEM – the first to feature electron transfer dissociation, a fragmentation technique that preserves post-translational modifications and provides unique capabilities for PTM discovery.

ESI-TOF - FOR THE STUDY OF SMALL MOLECULES, PROTEINS AND PROTEIN COMPLEXES

The micrOTOF, micrOTOF-Q and BioTOF series of ESI-TOF and ESI-Q-q-TOF mass spectrometers provide the highest resolution and mass accuracy in both MS and MS/MS mode for the study of small molecules, proteins and protein complexes.

MALDI-TOF - DETAILED PROTEIN CHARACTERISATION, WITH MEDIUM TO HIGH SAMPLE THROUGHPUT

Microflex and microflex LT - superior 15k resolution and microScout MALDI targets in 1/4 MTP format distinguish the microflex from other benchtop MALDI-TOF systems. The modular design supports different and growing user requirements.

autoflex III smartbeam - the robust and reliable MALDI-TOF and TOF/TOF MS are ideal for detailed protein characterisation, high-resolution MALDI Imaging and validated biomarker discovery. These products feature patented smartbeam laser technology.

ultraflex III TOF/TOF with smartbeam technology – newly enabled for fastest LC-MALDI data acquisition, this instrument features the latest advancements in the sensitivity, resolution and mass accuracy of MALDI-TOF and TOF/TOF technology for high-success expression proteomics and advanced biomarker discovery studies. Smartbeam is the ideal laser technology for cutting-edge research in MALDI imaging. Other applications like large proteins or clinical proteomics also benefit from the smartbeam performance enhancements.

FTMS - ULTIMATE PERFORMANCE IN METABOLITE ID AND TOP-DOWN PROTEOMICS

apex ultra - hybrid Qq-FTMS with ultra-high resolution and accurate mass for ultimate performance in proteomics including ECD and IRMPD. Low maintenance refrigerated magnets with field strengths of up to 15t are available. The apex series features unrivalled analytical performance: 900,000 resolving power (7t), sub-fmol sensitivity and sub-ppm mass accuracy for ultimate analytical claims.

apex IV - delivers 1ppm (internal calibration) mass accuracy and MS(n) for structure elucidation and confirmation. 4.7t and 7t magnets are available for ultra-high performance FTMS.

ROBOTICS

• PROTEINEER spII automated spot picker for gel-based proteomics
• PROTEINEER dp digest and prep workstation for gel-based proteomics
• PROTEINEER fc LC-MALDI fraction collector
• ClinProtRobot prep station for biomarker discovery
• PureDisk workstation for SNP genotyping

CONSUMABLES

CARE products are designed for supporting our customers with high-quality consumables, accessories and dedicated kits. Our CARE product range is specifically optimised and certified for all Bruker Daltonics systems. Our solutions include:

CLINICAL PROTEOMICS: MASS SPECTROMETRY-BASED BIOMARKER ANALYSIS

CLINPROT is an integrated set of tools for biomarker discovery and clinical proteomics research. Offering established methodologies and techniques for advanced clinical research, and shortening timelines in biomarker discovery, the MALDI MOLECULAR Imager is a complete system for MALDI Imaging. The MALDI BioTyper enables mass spectrometry-based microorganism identification.

PROTEINEER: MASS SPECTROMETRY-BASED PROTEOMICS SUITE

The PROTEINEER is an integrated hardware and software suite for automated protein identification and characterization from 2D gels.

PROTEINEER-LC: LC-MS/MS-BASED PROTEOMICS SUITE

The PROTEINEER-LC is a comprehensive, integrated platform supporting all major LC-based proteomics strategies like LC-MALDI and LC-ESI-MALDI.

METABOLIC PROFILER: THE IDEAL TOOL FOR METABOLIC STUDIES

Metabolic profiler is an integrated platform for metabolism studies and analysis of complex mixtures. This product features an HPLC microTOF™ ESI-TOF system, an optional Avance NMR spectrometer, and software for data acquisition, evaluation and statistical analysis for applications.

GENOLINK: MASS SPECTROMETRY-BASED GENOTYPING SOLUTION

The GENOLINK is an integrated analytical platform for functional genomics, designed to interface with the PROTEINEER suite.

FACILITIES

Development and production sites are situated in the US and Germany. An international network of sales, applications and service centres and qualified distributors supports our worldwide activities.