Bruker Daltonics Announces Two Application Notes Demonstrating its Leading Mass Spectrometry Performance in the 2006 ABRF Proteomics Studies
28 May 2006
At the 2006 ASMS conference, Bruker Daltonics will announce two new application notes on the results of this year's Assocation of Biomolecular Research Facilities' (ABRF) proteomics studies. In the Protein Standards Research Group (sPRG) identification study, as well as in the Proteomics Research Group (PRG) quantification study, information obtained with solutions and instrumentation from Bruker Daltonics has achieved the top scores.
In the quantification study, the results submitted by Bruker Daltonics (code 27960v) produced the highest result among the commercially available isotopic labelling technologies. All mass spectra were obtained on a Bruker Daltonics ultraflex™ II MALDI-TOF/TOF mass spectrometer, using the ICPL duplex quantitation kit available from Bruker Daltonics, and were analysed using the Company's WARP™-LC quantification software.
In the sPRG identification study, data from the Bruker Daltonics HCTultra™ ion trap (code 77708v) and ultraflex II (code 27960v) were analysed. The HCTultra was the highest-performing instrument in this study (100% accuracy, 98% specificity) and the ultraflex II ranked eighth among 74 participants turning in results. Both instruments provided an average number of peptides / protein of 11.5 and 11, which are the best results among all participating vendors.
Dr. Carsten Baessmann, Head of ESI Applications Development at Bruker Daltonics, said: "We are quite proud to report the results of the sPRG study which confirms again that our HCTultra high-capacity ion trap is indeed the performance leader in nanoLC/MS/MS for proteomics."
Dr. Arnd Ingendoh, Assistant Vice President for Proteomics at Bruker Daltonics, added: "Our proteomics customers are particularly excited about our novel WARP-LC 1.1 quantification software which, together with ICPL, is very successful in protein quantification. The LC-MALDI approach using our ultraflex II TOF/TOF has again proven its top performance, when combined with these innovative isotope labelling and analysis tools."
