Bruker Daltonics Introduces Unique TargetAnalysis™ Solution for Multi-target Screening in Forensics, Environmental
03 June 2007
At the 55th ASMS Conference on Mass Spectrometry, Bruker Daltonics announced the launch of its novel TargetAnalysis™ application software for multi-target compound screening in complex matrices, providing much increased specificity and enhanced SigmaFitTM molecular formula determination.
TargetAnalysis is a library-based screening software solution able to screen hundreds of compounds from a single sample LC/ESI-TOF run with the ultra stable outstanding mass accuracy provided by Bruker's micrOTOFTM or micrOTOF-QTM mass spectrometers.
Using Bruker's unique ESI-TOF technology with intrinsically outstanding mass accuracy and excellent stability over time, over concentration changes during an LC-run, as well as over a wide mass range, scientists can now screen for large compound libraries with a confidence level and reproducibility unsurpassed by any other system.
In contrast to traditional triple-quadruple mass spectrometers which are limited in the number of targets they can screen per LC run, the micrOTOF TargetAnalysis solution can easily handle several hundred compounds in a single LC run. This easy and robust workflow saves significant time when running multi-target applications like drugs/metabolites in urine, food safety analysis, forensic toxicology or environmental testing.
Dr. Ian Sanders, Executive Vice President of Bruker Daltonics, commented: "With the launch of TargetAnalysis, Bruker Daltonics opens up an exciting application area for our unique ESI-TOF micrOTOF and micrOTOF-Q systems. With this novel screening software, our customers can now automatically create their own application-specific accurate mass libraries, for example, for pesticides in food or in doping control.
"Our unique AMIC (accurate mass ion chromatogram) technique, with a tolerance down to ± 0.002 Da, dramatically reduces chemical background interference and greatly improves specificity. In addition, retrospective in silicon screening for new or unexpected compounds is possible because unlike in triple-quad based MRM methods, we retain the full molecular information content in addition to the target library specific information."
