New biomarker development, based on changes in kinase activity, is at the root of PamGene's drive towards making 'companion diagnostics' a reality. Using these new biomarkers, PamGene's technology platform can measure the effect of a drug on kinase activity in the patient's own tissue (a biopsy) prior to treatment.
In other words, strong hints about the likelihood of a cancer drug's effectiveness in that patient can be obtained before initiating treatment. This has important implications for patient treatment, clinical trials, and for the agencies that finance drug therapy.