Alpha Diagnostic International - Protein and Gene Sequence Analysis

Alpha Diagnostic provides a comprehensive range of services related to protein or gene sequence analyses for the purpose of selecting antigenic peptides, synthesis of custom peptides, antibodies to peptides and proteins.

PHOSPHOPEPTIDE, PEPTIDE AND PROTEIN ANTIBODIES

ADI specializes in producing antibodies to phosphopeptides and acetylated peptides or proteins. ELISA testing of antibodies and affinity purification of antibodies is also available. ADI has been one of the most cited commercial sources for these services for the last 15 years.

PRIMARY ANTIBODIES

ADI has also produced thousands of primary antibodies for tumour markers, drug metabolizing enzymes, membrane receptors, growth factors, and drug transporter proteins.

ELISA KITS FOR SERUM PROTEINS

ADI has hundreds of ELISA kits for human and animal proteins, and it is the most comprehensive sources of autoimmune ELISA kits for animal research. ADI has recently produced recombinant proteins, antibodies, and ELISA kits for anthrax vaccine research.

ADI is also the source of monkey-specific antibodies and ELISA kits for IgG, IgA, IgM, IgE and other serum proteins. Highly economical ELISA readers and washers are also available.

CUSTOM PEPTIDE SYNTHESIS, ANTIBODIES AND PURIFICATION

ADI uses the latest technology in peptide synthesis using fmoc / tboc chemistries to synthesize custom peptides to your specification (purity, quantities, etc.). We perform rigorous quality controls (mass specs, hplc, amino acid analyses, etc.) at various stages of peptide synthesis.

Most common peptide modifications (phosphorylation, acetylating etc) are available. ADI can also synthesize long peptides (~100 AA).

ADI offers one of the most comprehensive services for the selection of antigenic peptides, BLAST searches, and identification of signal peptide, trans-membrane domains, sequence alignment, and other common structural motifs. Antigenic peptides can then be used for antibody production.

ADI has its own USDA-approved animal research facility for custom production of antibodies in rabbits, goats, mice, pigs and chickens. Purified peptides proteins (recombinant GST, His-tag, etc.) are used for antibody production.

Antibodies are tested by ELISA or other techniques (Western, IHC, etc.) upon request. ADI specializes in producing antibodies to modify peptides (phosphorylated and acetylated peptides, etc.).

PRIMARY AND COMMON FUSION TAG ANTIBODIES

ADI produces and distributes an extensive range of antibodies, covering the fields of obesity, circadian rhythm, ageing, cell cycle, apoptosis, drug metabolizing enzymes and drug transporters, DNA repair, viral proteins; energy metabolism and body-weight regulation; dialectology; cytokines, chemokines and related molecules; bone and cartilage metabolism; cardiovascular disease; and growth hormone and factor-related products, enzymes and hormones, and allergens.

ADI provides the most extensive collection of common fusion tag antibodies (GST, His, MBP, Myc-tag, etc.). Recombinant proteins containing the appropriate tags are also available for control studies.