Biotage - Microwave Synthesis and Flash Purification Instrumentation and Consumables

Biotage offers a full range of solutions, from synthesis to purification, designed to fulfill the needs of medicinal, analytical and process chemists. These include the Initiator microwave synthesizer, the Pathfinder online microwave synthesis method database, flash cartridges, the SP1 flash purification system and ISOLUTE® sample preparation (SPE) products.

MICROWAVE SYNTHESIZER AND MICROWAVE VIALS

Initiator is a flexible microwave synthesizer for fast, safe and scalable synthesis, tailored for medicinal chemistry. The new, compact design of the Initiator microwave synthesizer is 45% smaller than its predecessors. Chemists can load and run samples in just a few simple steps using the new embedded touch-screen control and graphical-user-interface.

With the EXP upgrade, the system can run 0.2mL to 20mL vials. For automated operation, an eight- or 60-position robotic assembly can be added at any time. All Biotage microwave synthesizers are designed to operate at elevated temperatures and pressures with best-in-class safety features.

BIOTAGE PATHFINDER WEB - ONLINE MICROWAVE REACTION DATABASE

Biotage Pathfinder Web is the world’s largest online database of established methods for microwave synthesis. The new web-based format offers chemists worldwide access to more than 3,800 diverse microwave methods. Using a simple keyword and/or substructure search, it is fast and easy to find microwave conditions for your reactions, along with experimental details.

Monthly updates are contributed from scientific partners and recent literature. Reactions are checked for accuracy and ambiguous processes are verified with authors directly, a level of crosschecking unique to the PathFinder.
www.biotagepathfinder.com

BIOTAGE FLASH CARTRIDGES™ - IMPROVE YIELD, PURITY AND REPRODUCIBILITY

Developed in 1999, Biotage FLASH+ cartridges, compression modules, and Samplet™ cartridges have quickly set the standards by which all other flash cartridge technologies are compared.

The FLASH+ cartridge is the only cartridge platform that allows five different sample loading options. A recessed inlet design accommodates Samplet™ cartridges for improved sample introduction and separation. High performance compression modules increase pressure tolerances up to 100psi. Available in six dimensions and five stationary phases (KP-SIL™, KP-NH™, KP-C18-HS™, KP-C18-WP™ and KP-C4-WP™), this versatile purification tool enables chemists to purify even the most challenging crude samples.

SP1 FLASH PURIFICATION SYSTEM - REDUCE THE TIME NEEDED TO ACHIEVE SUCCESSFUL SEPARATIONS

The new SP1 flash purification system with Touch Logic Control™ takes automated flash purification to the next level, enabling chemists to load and run samples in three simple steps. Biotage systems operate at higher pressures using patented technology, increasing flow-through and reducing purification time. A unique, automated method creation feature quickly creates sample-specific methods using TLC data. Built-in solvent monitoring, pressure control and fraction arm positioning ensure sample safety, eliminating any loss due to malfunction. Automating the purification process using a Biotage SP1 reduces the time needed to achieve successful separations.

ISOLUTE® SAMPLE PREPARATION (SPE) PRODUCTS

ISOLUTE® SPE products are a range of leading quality SPE columns and 96-well plates, packed with a variety of ISOLUTE non-polar, mixed-mode and ion exchange sorbents. Designed to extract drugs from biological fluid samples, a range of retention mechanisms are available, along with technical notes that detail how to use each sorbent type.

All ISOLUTE SPE sorbents are available packed into standard or tab-less SPE columns, ideal for many manual and automated SPE procedures. For higher throughput applications, industry standard fixed well ISOLUTE-96 extraction plates, or versatile ISOLUTE Array® wells and plates are available. ISOLUTE Array plates can be populated with up to 96 individual Array wells, to match the number of samples to be extracted.

Accelerate synthesis. Accelerate purification.