White Papers

Orthotopic and metastasis models for preclinical efficacy testing of novel cancer drugs

Pharmatest Services

Lack of efficacy is one of the major causes of attrition in the clinical development of new compounds to treat cancer.

Orthotopic and metastasis models for preclinical efficacy testing of novel cancer drugs

The ImmunoPrecise Rapid Prime System Reduces the Immunization Stage of Hybridoma Production to 18 Days

ImmunoPrecise Antibodies

The ImmunoPrecise Rapid Prime System Reduces the Immunization Stage of Hybridoma Production to 18 Days

The ImmunoPrecise Rapid Prime System Reduces the Immunization Stage of Hybridoma Production to 18 Days

Sartorius Lab Instrument's Cubis® Balance Range Meets the Cleanability Requirements of the Pharmaceutical Industry

Sartorius

Balances in Satorius Lan Instrument's Cubis® product range have been designed for the demanding pharmaceutical environment, which is regulated by good manufacturing practices (GMP) and good laboratory practices (GLP).

Sartorius Lab Instrument's Cubis® Balance Range Meets the Cleanability Requirements of the Pharmaceutical Industry

Case Study: Compaction Behaviour of Orally Dispersable Mini-Tablets

Gamlen Instruments

This whitepaper describes a method for performing dynamic powder compaction analysis and for measuring tensile fracture strength of tablets.

Case Study: Compaction Behaviour of Orally Dispersable Mini-Tablets

Clinical Trial Consulting, Pharmaceutical Consulting and Adaptive Clinical Trial Design

Pharmaceutical Development Group

Clinical trial consulting and pharmaceutical consulting professionals will benefit by becoming current on adaptive trial design.

Clinical Trial Consulting, Pharmaceutical Consulting and Adaptive Clinical Trial Design

Stability Analysis of Proteins for the Biopharmaceutical Industry

Malvern Instruments

The biggest class of biopharmaceuticals on the market is monoclonal antibodies (mAb) and their specific binding nature provides an opportunity to use them to modulate pharmaceutically-relevant molecule activity to control or prevent disease.

Stability Analysis of Proteins for the Biopharmaceutical Industry

Benefits of Trehalose

Pfanstiehl

Products such as monoclonal antibodies (mAb), fusion proteins, peptides, vaccines, antibody drug conjugulates (ADC) and stem cells benefit from the stabilising effects of Trehalose.

Benefits of Trehalose

Softigel by Procaps Brochure

Softigel

Procaps is one of the world's largest softgel companies, specialising in the production and development of advanced gelatin-related technologies.

Softigel by Procaps Brochure

Processability Assessment of Crystal Habit-Modified Active Pharmaceutical Ingredients

Gamlen Instruments

The efficiency of downstream processing of active pharmaceutical ingredients (API) can depend on their particulate properties, including size and shape.

Processability Assessment of Crystal Habit-Modified Active Pharmaceutical Ingredients

Validated Metal Analysis

Pfanstiehl

Four commonly utilized carbohydrates for ptotein stabilization are Sucrose, Trehalose, Mannitol, and Maltose.

Validated Metal Analysis

Gold Nanoparticle Applications and Characterisation by Nanoparticle Tracking Analysis

Malvern Instruments

Gold nanoparticles are one of the most popular and extensively researched type of nanoparticle.

Gold Nanoparticle Applications and Characterisation by Nanoparticle Tracking Analysis

Application: Operating Reactor Systems for Process Research and Development

SYSTAG Systems Technik

In this case study, three reactor systems (FlexyCUBE 70ml, FlexyPAT 2l, and ChemTeacktor 25l) are operated on the same PC using application software FlexySys.

Application: Operating Reactor Systems for Process Research and Development

Innovator or Generic, All Roads Lead to the 505(b)(2)

Pharmaceutical Development Group

Faced with decreasing R&D output, billions of dollars in patent expirations and increasing generic competition, innovators are forced to re-evaluate traditional business models.

Innovator or Generic, All Roads Lead to the 505(b)(2)

From Gene to Finished Vial

Biovian

Biovian is a one-stop-shop in GMP contract manufacturing of biopharmaceuticals, covering services from early development to finished vial.

From Gene to Finished Vial

Stability Issues Related to Soft Gelatin Capsule Development

Softigel

Stability issues are a challenge for formulators. The reactivity of formulations depends on many factors, although it is generally recognised that labile drugs in aqueous forms are sometimes the worst cases.

Stability Issues Related to Soft Gelatin Capsule Development

Paradigm Shift Regarding API and Formulation Components

Pfanstiehl

This whitepaper will provide an introduction to high-purity carbohydrates often used for applications such as stabilisation, modulation, and cryopreservation, comparing the old paradigm that formulation components are inactive ingredients with limite...

Paradigm Shift Regarding API and Formulation Components

Optimising Development Resources for Efficient Product Development

SYSTAG Systems Technik

Development departments suffer from a shortage of resources and are often overburdened with administration tasks.

Optimising Development Resources for Efficient Product Development

Gamlen Study: Breaking Anisotropic Rod-Shaped Particles

Gamlen Instruments

Gamlen presents a study conducted by V. Penkavova1, L. Kulaviak1, M.C. Ruzicka1, M. Puncochar, and P. Zamostny on the 'Beaking of Anisotropic Rod-Saped Particles'.

Gamlen Study: Breaking Anisotropic Rod-Shaped Particles

FlexyPAT as a Calorimeter

SYSTAG Systems Technik

FlexyPAT is a modular process automation technology that enables automated, customer-specific lab reactor systems to be implemented cost-effectively. With FlexyPAT, you have a strong and flexible tool.

FlexyPAT as a Calorimeter

Customised Crystallisation and Filtration System

SYSTAG Systems Technik

Systag's crystallisation and filtration system helps increase your flexibility, productivity, and optimises your documentation.

Customised Crystallisation and Filtration System

Drug Labeling Specialist on New Pregnancy Labeling Rules

Pharmaceutical Development Group

On 30 June, 2015, new pregnancy labeling rules for prescription drugs took effect, marking the demise of pregnancy categories (A, B, C, D, X), which have been in use since 1979.

Drug Labeling Specialist on New Pregnancy Labeling Rules