White Papers

Using FlexyCUBE in Risk and Quality Analysis

SYSTAG Systems Technik

In the first reaction step, an acid is added with constant thermal reduction (TR) control and stirrer speed.

Using FlexyCUBE in Risk and Quality Analysis

Validated Metal Analysis

Pfanstiehl

Four commonly utilized carbohydrates for ptotein stabilization are Sucrose, Trehalose, Mannitol, and Maltose.

Validated Metal Analysis

Benefits of Trehalose

Pfanstiehl

Products such as monoclonal antibodies (mAb), fusion proteins, peptides, vaccines, antibody drug conjugulates (ADC) and stem cells benefit from the stabilising effects of Trehalose.

Benefits of Trehalose

From Gene to Finished Vial

Biovian

Biovian is a one-stop-shop in GMP contract manufacturing of biopharmaceuticals, covering services from early development to finished vial.

From Gene to Finished Vial

Stability Analysis of Proteins for the Biopharmaceutical Industry

Malvern Instruments

The biggest class of biopharmaceuticals on the market is monoclonal antibodies (mAb) and their specific binding nature provides an opportunity to use them to modulate pharmaceutically-relevant molecule activity to control or prevent disease.

Stability Analysis of Proteins for the Biopharmaceutical Industry

Using Differential Scanning Calorimetry in Lipid Bilayer Membranes to Characterise Thermotropic Phase Transitions

Malvern Instruments

Proteins and other constituents are bound or incorporated into cell membrane surface bilayers formed by lipids.

Using Differential Scanning Calorimetry in Lipid Bilayer Membranes to Characterise Thermotropic Phase Transitions

Go Beyond With Your Discoveries with Softigel Product Development and Contract Manufacturing Services

Softigel

Part of the Procaps Group and one of the world's largest manufacturers, Softigel shows its deep knowledge of gelatin formation in its softgels expertise.

Go Beyond With Your Discoveries with Softigel Product Development and Contract Manufacturing Services

Save Money with the Mastersizer 3000

Malvern Instruments

Certain practical criteria must be met by an instrument to be used in today's busy analytical laboratories. It must also stand-up to rigorous economic evaluation.

Save Money with the Mastersizer 3000

Reasons to Replace Your Viscometer with a Rheometer

Malvern Instruments

It may be time to assess what a modern rheometer can do, especially in comparison to a viscometer.

Reasons to Replace Your Viscometer with a Rheometer

Using Isothermal Tirtration Calorimetry to Perform Biophysical Characterisation of Epigenetic Protein Interactions with Chromatin

Malvern Instruments

Epigenetics is the study of heritable changes in gene expression caused by non-genetic mechanisms, without alternations in gene structure or DNA sequence.

Using Isothermal Tirtration Calorimetry to Perform Biophysical Characterisation of Epigenetic Protein Interactions with Chromatin

Preformulation and Stability Studies of Biotherapeutics by DSC

Malvern Instruments

Treating diseases using Biothermics is a rapidly growing field, often requiring high-concentrations and multiple doses.

Preformulation and Stability Studies of Biotherapeutics by DSC

Critical Containment Products for the Pharmaceutical Industry

PBSC

Due to its relationship with US-based Presray, PBSC has been able to expand its product range for the laboratory and cleanroom settings and the two company's product ranges complement each other.

Critical Containment Products for the Pharmaceutical Industry

Micrometirics Product Brochure

Micromeritics

The physisorption line is designed to measure surface area and porosity for a wide range of materials, determining the quality and utility.

Micrometirics Product Brochure

Sartorius Lab Instrument's Cubis® Balance Range Meets the Cleanability Requirements of the Pharmaceutical Industry

Sartorius

Balances in Satorius Lan Instrument's Cubis® product range have been designed for the demanding pharmaceutical environment, which is regulated by good manufacturing practices (GMP) and good laboratory practices (GLP).

Sartorius Lab Instrument's Cubis® Balance Range Meets the Cleanability Requirements of the Pharmaceutical Industry

Using Different Scanning Calorimetry to Accelerate Biotherapeutic Process Development

Malvern Instruments

Purification and production of immunoglobulins of the gamma isotope for therapeutic or diagnostic applications is commonly used, particularly human IgG1.

Using Different Scanning Calorimetry to Accelerate Biotherapeutic Process Development

Use of Fully Automated Scattering Techniques to Identify Protein Formulations

Malvern Instruments

To meet commercial targets, fully-automated light scattering techniques are sometimes used in the identification of proteins.

Use of Fully Automated Scattering Techniques to Identify Protein Formulations

Pharmaceutical Consulting and Generic Drug Professionals

Pharmaceutical Development Group

On November 13, 2013, FDA proposed a new rule known as the 'Supplemental Applications Proposing Labelling Changes for Approved Drugs and Biological Products'.

Pharmaceutical Consulting and Generic Drug Professionals

Binding Thermodynamics of Substituted Diaminopyrimidine Renin Inhibitors

Malvern Instruments

ACE inhibitors reduce blood pressure by inhibiting production of the potent vasoconstrictor angiotensin II and ARB inhibitors block binding of angiotensin II to the angiotensin receptor.

Binding Thermodynamics of Substituted Diaminopyrimidine Renin Inhibitors

Paediatric Clinical Trials 2016

SMI

Paediatric Clinical Trials 2016 - enhancing your paediatric strategy in line to maximise clinical benefits for patients.

Paediatric Clinical Trials 2016

Bioneer Biomarker Services

Bioneer

The attached white paper is a presentation from Bioneer, which provides more information about the company and the services it provides, including immune bioactivity human DCs, biomarkers and molecular histology.

Bioneer Biomarker Services

Measurement of Pharmaceutical Lubricants Using the TriStar II Krypton Option

Micromeritics

A major advantage of using the TriStar II with the krypton option is the ability to measure low surface areas.

Measurement of Pharmaceutical Lubricants Using the TriStar II Krypton Option