Making the Most of Your Scale Down Model11 November 2011 by Fujifilm Diosynth Biotechnologies
While process understanding can come from a variety of sources - including early process development activities, experience with similar products and manufacturing campaigns for clinical supply - scaled down process models of unit operations have particular utility. Advantages such as ease of set up compared with pilot or full scale activities, smaller requirement for materials and possible automation through the use of robotics allow for a depth and span of investigation that is impractical at larger scale.
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Making the Most of Your Scale Down Model