Malvern Instruments

Biopharmaceutical and Drug Development

An Analysis of Antibodies Using Multi-Detector SEC Methodology

Malvern Instruments

Antibodies' innate ability to direct their neutralisation attacks toward specific components in harmful agents has generated a large amount of interest within the pharmaceutical industry.

Since much of an antibody's functionality depends on its molecular structure and integrity, full characterization, including molecular weight, size, and purity of these materials is critical to ensure efficacy

Size-exclusion chromatography (SEC), also referred to as gel permeation chromatography (GPC), is a widely used technique to characterise a range of samples, from bulk manufactured materials to proteins and other biological macromolecules, such as antibodies.

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