Custom Synthesis, Asymmetric Chemistry and Co-Crystallisation
Cocrystals in the Pharmaceutical and Fine Chemicals Industry: From an Option to an OpportunityEnantia
In the drug discovery and development arena it is well known that the choice of the right solid form can have a dramatic influence on the successful development of an active pharmaceutical ingredient (API).
Solid forms can shape the pharmacokinetic and formulation properties of a drug candidate to such an extent that the right solid form can be key to the success of the project. A suboptimal one can even compromise the whole project.
Therefore, to avoid unpleasant surprises during the development phases of a product, it is strongly recommended to address solid form studies in the early phases, even when a molecule is still in the discovery stage.
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