Cocrystals in the Pharmaceutical and Fine Chemicals Industry: From an Option to an Opportunity15 March 2012 by Enantia
In the drug discovery and development arena it is well known that the choice of the right solid form can have a dramatic influence on the successful development of an active pharmaceutical ingredient (API).
Solid forms can shape the pharmacokinetic and formulation properties of a drug candidate to such an extent that the right solid form can be key to the success of the project. A suboptimal one can even compromise the whole project.
Therefore, to avoid unpleasant surprises during the development phases of a product, it is strongly recommended to address solid form studies in the early phases, even when a molecule is still in the discovery stage.
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Cocrystals in the Pharmaceutical and Fine Chemicals Industry: From an Option to an Opportunity