New Features information at Drug Development Technology New and updated information from Features listed on en-us New Features information at Drug Development Technology February's top stories: Merck's Phase III HIV-1 trial results, NIH's Phase I AGS-v vaccine trial Merck reported positive results from the Phase III trial of its non-nucleoside reverse transcriptase inhibitor (NNRTI) doravirine (MK-1439) for the treatment of patients with HIV-1 infection, and NIH's NIAID initiated a Phase I trial of vaccine AGS-v… Tue, 07 Mar 2017 00:00:00 GMT January's top stories: TG Therapeutics' Phase II trial, antidepressant hip fracture risk TG Therapeutics began its Phase II investigator initiated trial of TGR-1202 in combination with ibrutinib to treat Diffuse Large B-cell Lymphoma (DLBCL), and a study suggested that antidepressant usage increases the risk of hip fracture. Drugdevelopm… Mon, 06 Feb 2017 00:00:00 GMT 2016: The year's biggest Drug Development Technology stories NIAID began a new HIV vaccine study in South Africa and Eli Lilly’s Phase III trial of Alzheimer disease drug failed. Drugdevelopment-technology wraps-up the key headlines from 2016. Tue, 03 Jan 2017 00:00:00 GMT November’s top stories: Wellcome’s clinical trial network, Eli Lilly’s Alzheimer disease drug trial UK’s Wellcome recommended a clinical trial network for efficient drug development, and Eli Lilly’s Alzheimer disease drug trial failed to meet endpoints. wraps up the key headlines from November. Tue, 06 Dec 2016 00:00:00 GMT October’s top stories: Eurocine Vaccines initiated influenza vaccine study, IVF usage led to conceiving male child Eurocine Vaccines initiated a Phase I/II influenza vaccine study and a new study suggested in-vitro fertilisation increases the chances of conceiving a male child. wraps up the key headlines from October 2016. Mon, 07 Nov 2016 00:00:00 GMT September's top stories: Oncternal begins TK216 trial, Medical cannabis trials begin in Canada Oncternal Therapeutics began dosing patients in its Phase I clinical trial of TK216 to treat Ewing sarcoma and Tilray and University of British Columbia began patient enrolment in Canada’s first Phase II clinical trial of medical cannabis to treat po… Thu, 06 Oct 2016 23:00:00 GMT August's top stories: Gradalis' Phase I breast cancer trial, Biothera and Merck conducted combination cancer immunotherapy trials Gradalis dosed the first patient in its pilot Phase I trial of a combination of Vigil Engineered Autologous Tumour Cells (EATCs) and durvalumab to treat advanced breast cancer, and Biothera collaborated with Merck to expand the ongoing clinical progr… Thu, 08 Sep 2016 23:00:00 GMT Pharma Technology Focus – Issue 50 In this issue: Maximising investment by cancer megafunds, positive clinical trials for an antibody to treat lupus, how copper can be used to tackle obesity, whether day and night should influence our drug regimes, a device to soak up excess drugs and… Thu, 25 Aug 2016 10:46:00 GMT July's top stories: GBT's Phase II1 trial GBT440, Merck's Phase III trial ONCEMRK of Isentress Global Blood Therapeutics (GBT) began the Phase IIa trial (GBT440-007) of GBT440 in adolescents with sickle cell disease (SCD), and Merck reported positive results from its ongoing Phase III pivotal trial ONCEMRK of Isentress (raltegravir) to treat a… Mon, 08 Aug 2016 23:00:00 GMT June's top stories: Bayer reported positive results of RESORCE trial, TapImmune initiated Phase II trial of TPIV 200 Bayer reported positive results from the Phase III RESORCE trial of Stivarga (regorafenib) tablets to treat unresectable hepatocellular carcinoma, and TapImmune initiated its Phase II trial of cancer vaccine TPIV 200. w… Tue, 05 Jul 2016 23:00:00 GMT May's top stories: ProMedica began human stem cell trial, Cerulean dosed in Phase l/ll combination trial ProMedica and Stemedica planned to begin a human stem cell trial for traumatic brain injury and Cerulean dosed its first patient in a Phase l/ll combination trial of CRLX101 and lynparza. wraps up the key headlines from… Mon, 06 Jun 2016 23:00:00 GMT April's top stories: SynbiCITE's synthetic biology foundry, Omeros's phase II clinical trial of OMS721 SynbiCITE opened a commercial synthetic biology foundry at Imperial College London, and Omeros began dosing patients in its new Phase ll clinical trial of OMS721 in corticosteroid-dependent renal diseases. wraps up the … Wed, 04 May 2016 23:00:00 GMT March's top stories: Tracon's Phase IbTRC105 clinical trial, ADC begins ADCT-402 trial Tracon Pharmaceuticals started Phase Ib clinical trial of TRC105, a clinical stage antibody to endoglin, and ADC Therapeutics began a Phase I trial of its antibody drug conjugate (ADC) ADCT-402. wraps-up the key headlin… Mon, 04 Apr 2016 23:00:00 GMT Pharma Technology Focus – Issue 45 In this issue: Israel’s pharma market, what Brexit would mean for clinical research in the UK, developments in obstetrics, the trouble with inhalable insulin, the FDA’s new support for innovation in manufacturing, plant-based vaccine manufacturing an… Tue, 29 Mar 2016 14:15:00 GMT February's top stories: 60% of trial results not shared, Dilaforette-AGU team-up Yale School of Medicine researchers revealed about 60% of academic clinical trial results were not shared after completion, and Dilaforette and Arabian Gulf University were to collaborate on a Phase II proof-of-concept trial of sevuparin in patients … Mon, 07 Mar 2016 00:00:00 GMT Pharma Technology Focus - Issue 44 In this issue: Clinical trials in Russia, how understanding the microbiome could help with drug delivery, making the most of data analytics, the potential of wearable trackers in clinical trial data collection, the pharma industry's role in fighting … Mon, 22 Feb 2016 12:52:00 GMT January's top stories: Profectus Ebola trial, AstraZeneca-Incyte lung cancer drug Profectus BioSciences began VesiculoVax-vectored vaccine trial, AstraZeneca and Incyte announced combination drug evaluation, SillaJen started Phase III trial for Pexa-Vec. wraps-up the key headlines from January. Fri, 05 Feb 2016 00:00:00 GMT Pharma Technology Focus – Issue 43 In this issue: A look inside China’s pharmaceutical market, GSK’s pipeline to 2020, tackling the world’s most pressing clinical needs, new digital tools for clinical trials, a new approach to predicting side effects and more. Thu, 21 Jan 2016 16:45:00 GMT 2015: The year's biggest Drug Development Technology stories UK develops method to improve drug delivery in cancer treatment, skin cancer drug trial starts in UK, and Nestlé and EpiGen to assess impact of nutrients during pregnancy. Drug wraps up the key headlines from 2015. Tue, 05 Jan 2016 11:22:00 GMT November's top stories: Phase III trial of sirukumab, Lyrica fails trial GlaxoSmithKline begins Phase III trial of sirukumab, Pfizer's neuropathic pain drug Lyrica fails Phase III trial, and Seattle begins Phase I/II trial of SGN-CD33A. wraps up key headlines from November. Fri, 11 Dec 2015 11:58:00 GMT