New WhitePapers information at Drug Development Technology New and updated information from WhitePapers listed on en-us New WhitePapers information at Drug Development Technology Reasons to Replace Your Viscometer with a Rheometer It may be time to assess what a modern rheometer can do, especially in comparison to a viscometer. Fri, 22 Sep 2017 08:20:00 GMT Characterisation Information of Critical Excipients for Sourcing Critical Raw Materials The increasing complexity of large molecule and cell-based therapeutics calls for an evolution in our understanding of the impurity and functional contributions of each formulation component. Fri, 22 Sep 2017 08:19:00 GMT Application: Operating Reactor Systems for Process Research and Development In this case study, three reactor systems (FlexyCUBE 70ml, FlexyPAT 2l, and ChemTeacktor 25l) are operated on the same PC using application software FlexySys. Fri, 22 Sep 2017 08:19:00 GMT Processability Assessment of Crystal Habit-Modified Active Pharmaceutical Ingredients The efficiency of downstream processing of active pharmaceutical ingredients (API) can depend on their particulate properties, including size and shape. Mon, 18 Sep 2017 15:07:00 GMT Orthotopic and metastasis models for preclinical efficacy testing of novel cancer drugs Lack of efficacy is one of the major causes of attrition in the clinical development of new compounds to treat cancer. Mon, 18 Sep 2017 15:07:00 GMT Sartorius Lab Instrument's Cubis® Balance Range Meets the Cleanability Requirements of the Pharmaceutical Industry Balances in Satorius Lan Instrument's Cubis® product range have been designed for the demanding pharmaceutical environment, which is regulated by good manufacturing practices (GMP) and good laboratory practices (GLP). Mon, 18 Sep 2017 15:06:00 GMT Experienced Accessible Pharma Professionals and Global Regulatory Services PDG has experienced and accessible full-time professional staff and expert consultants including a multidisciplinary team of pharmacologists, toxicologists, clinicians, epidemiologists, statisticians, analytical scientists, regulatory professionals a… Mon, 18 Sep 2017 15:05:00 GMT From Gene to Finished Vial Biovian is a one-stop-shop in GMP contract manufacturing of biopharmaceuticals, covering services from early development to finished vial. Mon, 18 Sep 2017 15:05:00 GMT Benefits of Trehalose Products such as monoclonal antibodies (mAb), fusion proteins, peptides, vaccines, antibody drug conjugulates (ADC) and stem cells benefit from the stabilising effects of Trehalose. Thu, 14 Sep 2017 16:55:00 GMT Dyanamic Light Scattering - Common Terms Defined There are a number of sources of information that give a mathematical description of the terms used in light scattering. However, these will not usually give assistance in understanding their practical application. Thu, 14 Sep 2017 16:55:00 GMT Optimising Development Resources for Efficient Product Development Development departments suffer from a shortage of resources and are often overburdened with administration tasks. Thu, 14 Sep 2017 16:54:00 GMT The ImmunoPrecise Rapid Prime System Reduces the Immunization Stage of Hybridoma Production to 18 Days The ImmunoPrecise Rapid Prime System Reduces the Immunization Stage of Hybridoma Production to 18 Days Mon, 11 Sep 2017 11:23:00 GMT Go Beyond With Your Discoveries with Softigel Product Development and Contract Manufacturing Services Part of the Procaps Group and one of the world's largest manufacturers, Softigel shows its deep knowledge of gelatin formation in its softgels expertise. Mon, 11 Sep 2017 11:23:00 GMT Case Study: Compaction Behaviour of Orally Dispersable Mini-Tablets This whitepaper describes a method for performing dynamic powder compaction analysis and for measuring tensile fracture strength of tablets. Mon, 11 Sep 2017 11:22:00 GMT Stability Analysis of Proteins for the Biopharmaceutical Industry The biggest class of biopharmaceuticals on the market is monoclonal antibodies (mAb) and their specific binding nature provides an opportunity to use them to modulate pharmaceutically-relevant molecule activity to control or prevent disease. Thu, 07 Sep 2017 15:55:00 GMT Validated Metal Analysis Four commonly utilized carbohydrates for ptotein stabilization are Sucrose, Trehalose, Mannitol, and Maltose. Thu, 07 Sep 2017 15:54:00 GMT FlexyPAT as a Calorimeter FlexyPAT is a modular process automation technology that enables automated, customer-specific lab reactor systems to be implemented cost-effectively. With FlexyPAT, you have a strong and flexible tool. Thu, 07 Sep 2017 15:54:00 GMT A Guide Accross the Regulatory and Scientific Terrain Pharmaceutical Development Group (PDG) is a drug and medical device consultant that continuously engages in meetings and interactions with the US Food and Drug Administration (FDA). Tue, 05 Sep 2017 09:37:00 GMT Stability Issues Related to Soft Gelatin Capsule Development Stability issues are a challenge for formulators. The reactivity of formulations depends on many factors, although it is generally recognised that labile drugs in aqueous forms are sometimes the worst cases. Mon, 04 Sep 2017 08:30:00 GMT Paradigm Shift Regarding API and Formulation Components This whitepaper will provide an introduction to high-purity carbohydrates often used for applications such as stabilisation, modulation, and cryopreservation, comparing the old paradigm that formulation components are inactive ingredients with limite… Thu, 31 Aug 2017 15:24:00 GMT