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Genkyotex starts enrolment in Phase II trial of GKT831 to treat PBC
Gemphire reports positive top-line results from Phase IIb trial of HoFH drug
US-based Gemphire Therapeutics has reported positive top-line results from a Phase IIb clinical trial (COBALT-1) of gemcabene to treat patients with homozygous familial hypercholesterolemia (HoFH)....
Sitka Biopharma to initiate Phase I trial of STK-01 to treat bladder cancer
Verona to study RPL554 in Phase IIb trial for COPD in five European countries
UK-based biopharmaceutical firm Verona Pharma has secured regulatory approval to start a Phase IIb clinical trial of RPL554 in patients with chronic obstructive pulmonary disease (COPD) in the...
Teva and Xenon’s Phase II trial of TV-45070 for PHN fails to meet endpoints
Teva Pharmaceutical Industries and Xenon Pharmaceuticals have reported top-line data from a Phase II clinical trial of TV-45070 to treat patients suffering from post-herpetic neuralgia (PHN),...
Durect concludes enrolment in PERSIST trial of non-opioid analgesic
US-based biopharmaceutical company Durect has concluded patient enrolment in its Phase III PERSIST clinical trial of Posimir (Saber-Bupivacaine) for pain relief following...
Genentech and Epizyme to study tazemetostat in Phase Ib/II combination trial for NSCLC
Roche Group’s biotechnology subsidiary Genentech has expanded clinical collaboration with biopharmaceutical firm Epizyme to investigate the combination of atezolizumab (Tecentriq) and...
Xenetic Biosciences enrols first patient in Phase II trial of XBIO-101 for endometrial cancer
Bial and Eisai report positive results from Phase II trial of Zebinix for epilepsy
Bial and Eisai have reported a positive outcome from a Phase II clinical trial (Study 208) of Zebinix (eslicarbazepine acetate) in children with focal-onset...
DelMar Pharma to initiate Phase III trial of VAL-083 to treat GBM
CTD Holdings starts enrolment in Phase I/II trial of Trappsol Cyclo for NPC
Chi-Med commences Phase I/II trial of HMPL-453 for solid tumours
Hutchison China MediTech (Chi-Med) has commenced a Phase I/II clinical trial of HMPL-453 in China for the treatment of solid tumours in patients carrying fibroblast growth factor receptor...
Novartis reports positive top-line data from Phase III trial of cardiovascular drug
Novartis has reported positive top-line results from the Phase III CANTOS clinical trial of ACZ885 (canakinumab) and standard-of-care combination to address cardiovascular risk in patients...
Immune Pharma starts enrolment in Phase I/II trial of Ceplene for CMML
New Phase I/II trial indicates positive outcome for Astellas' cancer drug
US researchers at the University of Pennsylvania’s (Penn) Perelman School of Medicine and Abramson Cancer Centre have reported positive data from a Phase I/II clinical trial of...
InDex initiates enrolment for Phase IIb trial of cobitolimod to treat ulcerative colitis
Sweden-based InDex Pharmaceuticals has started patient enrolment in Phase IIb CONDUCT clinical trial of cobitolimod for treatment of patients with ulcerative...
Hansa Medical begins IdeS dosing in Phase II trial for anti-GBM antibody disease
Swedish biopharmaceutical firm Hansa Medical has begun dosing patients in its Phase II clinical trial of drug candidate IgG degrading enzyme of Streptococcus pyogenes (IdeS), to treat patients...
Genexine to conduct Phase Ib/II combination trial of cervical cancer drug GX-188E
Biotechnology firm Genexine has secured approval from the South Korean Ministry of Food and Drug Safety (MFDS) to conduct a Phase Ib/II trial of GX-188E vaccine in combination with...
Effector, Pfizer and Merck to initiate Phase II combination trial for colorectal cancer
Effector Therapeutics has signed a clinical collaboration and supply agreement with Pfizer and Merck to initiate a Phase II clinical trial of immuno-oncology drugs combination to...
Seattle Genetics stops Phase III trial of leukaemia drug due to high death rate
GSK’s Benlysta shows positive outcome in Phase II continuation trial for SLE
GlaxoSmithKline (GSK) reported positive data from the Phase II ten-year continuation clinical trial of Benlysta (belimumab) in combination with standard-of-care for patients suffering from...