Tissue Solutions High-Quality Human Tissues and Biological Materials
Tissue Solutions offers a single point of access to an entire range of human biological materials, including diseased and normal human tissues in fresh, frozen, and FFPE formats, and body fluids (e.g. blood, serum, plasma, CSF, ascites, urine, sputum, and synovial fluid). Using our large network of sources we find the tissues you require for drug discovery and development such as genomics, proteomics, biomarker studies, antibody testing, pharmacology and toxicology studies.
Banked human tissues – frozen tissues and formalin preserved paraffin embedded human tissues (FFPE)
We are not a ‘catalogue shop’. Instead, we can find the right tissues for your exact needs. Working with our network of post mortem and surgical excess sources, we supply fully consented frozen and FFPE blocks and can deliver large orders quickly.
Pathology verified tissues are available from a range of disease states (cancer, autoimmune, CNS / neurodegenerative, inflammation, metabolic, cardiovascular, blood disorders and infectious disease). We supply matched tumour and normal adjacent tissue from the same donor and meet your percentage tumour requirements. Surgical samples are typically frozen within 15-30min of resection and are usually supplied as blocks, although slides and TMAs are also available.
We supply the FDA / EMEA panel of normal tissues for cross-reactivity studies.
As we are not restricted by our inventory, we can find what you require. We stand by the quality of our samples and refund or replace unsatisfactory materials.
Fresh human tissues and cells
Tissue Solutions also provides fresh human tissues in a range of cancers for ex vivo and cell-based assays (surgical resections or post mortem). Fresh skin is also available from surgical excess following various cosmetic procedures. In addition, fresh urine and bloods can be delivered upon request from healthy and diseased volunteers.
We supply freshly isolated human primary cells – capillary brain endothelial cells, astrocytes and glial cells, human umbilical vein endothelial cells (P0), keratinocytes (pooled or single donor), fibroblasts, melanocytes, adipocytes, dermal microvascular endothelial cells, skeletal muscle cells, proximal tubular cells, pancreatic islets and hepatocytes (single donor). These can also be supplied in cryovials or flasks.
Bone marrow, umbilical cord, lipoaspirate dental pulp and adult human mesenchymal stem cells are also available, along with CD34 purified cells from umbilical cord blood.
Clinical collaborations for human tissue samples
If the specific samples you are looking for are not available, we can carry out a prospective collection with full ethics approval. We carry out feasibility studies to identify collaborating clinicians or clinical groups willing to collect on your behalf. We determine realistic protocols and associated timescales and provide realistic alternative approaches using different tissues types or experiments when needed.
For prospective collections we prepare the project plan, recruit collaborating clinicians, ensure ethics is in place and secure an agreement with the source.
Tissue processing and analysis services
We offer a range of tissue processing and analysis services through collaborating partners. This includes the more routine services such as DNA and mRNA extraction from both frozen and FFPE blocks plus the more specialist work as outlined below.
Immunohistochemistry (IHC) and histology services
As part of our IHC and histology services we offer specialist GLP-accredited provision of IHC and contract histology for expert antibody screening services covering all phases of clinical trials. We can also offer support for your therapeutic antibody development work through cross-reactivity studies in human tissue (FDA panel) and other species (GLP or non-GLP).
Primary cell line establishment and pancreatic islet studies
Working with experienced cell biologists we can establish and culture new primary cell lines derived from fresh human tissue. We also undertake pancreatic islet studies (studies on diabetes or for evaluating new drugs).
Development of non-invasive biomarkers
We can handle the development of non-invasive biomarkers, including sensitive gene expression profiling (qRT-PCR) measuring drug-induced changes in mRNA gene expression from individual hairs plucked from cancer patients undergoing treatment.
Products and Services
From the outset, Glasgow-based Tissue Solutions focused on meeting worldwide demand for ethically sourced human biomaterials.Read more
Tissue Solutions, one of the UK's leading providers of human biomaterials, has just received the prestigious Queen's Award for International Trade.Read more
Tissue Solutions has announced it has passed its annual continual assessment audit for ISO 9001 with BSI, demonstrating a commitment to continually improving its quality and management systems.Read more
Tissue Solutions Ltd, which sources human biomaterials for pre-clinical research, is celebrating having been in business for six years.Read more
Morag McFarlane, CSO at Tissue Solutions, is set to deliver a talk on Virtual Biobanks at the Biobanking Global Congress 2013 Europe.Read more
Tissue Solutions are delighted to announce the appointment of Dr Derek McFerran as a Business Development Director.Read more
Tissue Solutions to Exhibit at 2013 BIO International Convention, Booth 4438, Apr 22 – 25, 2013, in Chicago IL, US
Tissue Solution invites pharmaceutical and biotech companies to visit booth 4438 at this year's BIO International Convention 2013. We will be showcasing our unique tissue acquisition service and demonstrating the significant benefits of using high quality human tissue.Read more
Tissue Solutions has now been granted approval for a virtual sample collection, allowing researchers to request a range of samples on demand from ethically consented patients. These samples are available to both commercial and non-commercial organisations on approval of a project application.Read more
Tissue Solutions is moving to a new suite of offices at the West of Scotland Science Park having outgrown its current premises in Clydebank.Read more
Tissue Solutions are pleased to announce the addition of new members to the Tissue Solutions Research Governance Committee.Read more
Tissue Solutions is pleased to announce that it has been awarded ISO 9001:2008 BSI accreditation.Read more
Tissue Solutions, OracleBio and Histologix Join Forces to Provide Tissue to Data Biomarker Solutions
A new partnership provides tissue to data biomarker solutions. 'Our expertise provides your solutions' is the new motto being used as part of a unique and exciting partnership between three independent CROs in the life science sector.Read more
Tissue Solutions is pleased to announce a new email-based service designed to notify researchers of the availability of fresh human samples.Read more
Tissue Solutions is pleased to offer an exciting new human hepatoma cell line, HepaRG, for toxicology and ADME research (absorption, distribution, metabolism and excretion). Derived from a human liver progenitor cell line, HepaRG exhibits the characteristics of primary hepatocytRead more
Tissue Solutions is pleased to be able to offer human dorsal root ganglia (DRG) recovered under operating room conditions. DRGs contain the cell bodies of afferent neurons and are the mechanism by which the body detects and communicates pain through the central nervous system. The tissues are a tRead more
Tissue Solutions is pleased to announce a collaboration with CompanDX to deliver a bioinformatics service in support of personalised medicine and patient stratification. The partnership provides an unparalleled opportunity to link the supply of human tissues and biofluids to subsequent biomarkerRead more
Psoriasis is one of the most prevalent of all autoimmune diseases and the second most common skin diseases, the first being acne. 125 million people worldwide (2% to 3% of the total population) have psoriasis. Psoriasis is not a cosmetic problem. Nearly 60% of sufferers report their dRead more