During hemocompatibility testing, activation products may reach plateau values, which can result in less distinction between hemocompatible and hemo-incompatible materials.
Of concern is an underestimation of the blood activation caused by the biomaterial of interest, which may result in a false assessment of hemocompatibility.
To elucidate the optimal incubation time for in-vitro hemocompatibility testing, the scientists used the Haemobile circulation model with human whole blood taken from healthy volunteers, which was in-vitro incubated under pulsatile flow with physiological wall shear stress conditions.
This article was originally published on www.onlinelibrary.wiley.com/doi/10.1002/jbm.b.34326.
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