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APIs

Vaccine development: the need for speed

Lack of CMO availability threatens cell and gene therapy development

Novaliq’s NovaTears+Omega-3 represents the first-in-class omega-3-containing eye drop for evaporative dry eye

Approvals

FDA approves Opdivo/Yervoy combo treatment for kidney cancer

FDA grants fast track designation to Proteostasis CF therapy

Sanofi seeks EMA approval for asthma drug Dupixent

Clinical Research

TaiwanJ’s JKB-121 falls victim to unexpected placebo response in NASH patients

ILC 2018: NGM’s intravenous NASH therapy shows rapid reduction in liver fat content and fibrosis

Potential drug target for anti-obesity treatment discovered

Clinical Trials

TaiwanJ’s JKB-121 falls victim to unexpected placebo response in NASH patients

ILC 2018: NGM’s intravenous NASH therapy shows rapid reduction in liver fat content and fibrosis

Merck to begin two Phase III trials of PCV-15 (V114)

Diseases

TaiwanJ’s JKB-121 falls victim to unexpected placebo response in NASH patients

ILC 2018: NGM’s intravenous NASH therapy shows rapid reduction in liver fat content and fibrosis

Potential drug target for anti-obesity treatment discovered

Genomics & Proteomics

Lack of CMO availability threatens cell and gene therapy development

The age of immortality

CD47-targeted therapies: the breast cancer mop?

Market Data

CD40 agonist developments could support Anti-PD-(L)1 therapy in pancreatic cancer

ILC 2018: Madrigal Therapeutics’ MCL-3196 reduces liver fat in NASH patients

ILC 2018: Allergan’s cenicriviroc shows continued fibrosis response in NASH patients in two year extended study

Technology

Algorithm optimises peptides to target drug-resistant bacteria

Computer simulation offers digital penicillin production

Synthetic circuits and feedback loops enable bacteria to produce drugs

Online

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