Sucrose is a non-reducing crystalline disaccharide made up of glucose and fructose, found in many plants but extracted as ordinary sugar mainly from sugar cane and sugar beets.
Pfanstiehl brand, high-purity low endotoxin (HPLE) Sucrose is used in the biopharmaceutical industry to stabilise proteins, lipids, and carbohydrates throughout the formulation and freeze / thaw lifecycle of therapeutics.
It is also widely applied as a cryopreservative and media supplement in a variety of cell-based bioprocesses. It is preferred to trehalose in applications where solubility and/or viscosity issues are paramount.
The benefits of sucrose include but are not limited to:
• Monoclonal antibody (mAbs) stabilisation
• Media supplementation
• Antibody-drug conjugate (ADC) stabilisation
• Peptide stabilisation
• Stem cell preservation
• Vaccines stabilisation
Pfanstiehl Brand Sucrose is available as USP-NF (United States Pharmacopoeia – National Formulary), EP (European Pharmacopoeia) and JP (Japanese Pharmacopoeia). Pfanstiehl also holds a US DMF for the Sucrose (S-124-2-MC) product.